Thursday saw the delivery of a new Novartis drug: Tekturna (aliskiren). None of us had any idea what it was for, so we looked it up on Facts and Comparisons, and there was next to no information whatsoever, except that it is a “direct renin inhibitor” — whatever that meant.
Now that I’m home on a non-firewalled Internet connection, I can actually get real drug information. (How sad is it that I can’t do this at the pharmacy?) Aliskiren:
Aliskiren is a direct renin inhibitor, decreasing plasma renin activity (PRA) and inhibiting the conversion of angiotensinogen to Ang I. Whether aliskiren affects other RAAS components, e.g., ACE or non-ACE pathways, is not known
I’m sure you could play games targeting specific points and pathways in the renin-angiotensin-aldosterone system until the cows come home, but how many of them will be meaningful? Medscape has an article comparing, contrasting, and using Diovan and Tekturna in parallel:
Do we need Tekturna? Would not an ARB plus a diuretic do a better job? There are benefits to combining an ACEi with an ARB, that are fairly well understood. Is Tekturna going to create some sort of super trifecta?
I’m thinking not. Combining an ACEi with an ARB does a couple of things. First off, ACE inhibitors only stop the conversion of angiotensin I to angiotensin II. Blocking the pathway there does nothing to stop any non-specific binding to the angiotensin II receptor sites. ARBs block much of this non-specific binding because the receptor sites themselves are blocked. However ACEis also block the breakdown of bradkinin (which is broken down by ACE) which leads to greater vasodilation, which is why ACEis and ARBs are usually similar is study results. Bradykinins, of course, are a double-edged sword: they may contribute to vasodilation, but they are also responsible for the dry cough and angioedema associated with ACEis.
I don’t see how aliskiren is going to add to this. Is there component to the RAAS that I’m not thinking of? Is it not better to attack a problem from many different angles instead of hitting the same pathway three different ways?
Diovan HCT kept my bp under control for many years. Suddenly shot up in August 2007. Dr told me about a new drug called TekTurna that was supposed to work when others didn’t. Wow, it was great for about two weeks, but with side effects such as fatigue, coughing. Soon the Side effects were taking control of my life. Could hardly get out of bed, then they started decreasing. About the same time that the side effects decreased, BP has gradually gone back up, and the last two weeks has been WAY high, taking diovan AND tekturna. By the time I got to the Dr it was 184/120. Dr told me he wasn’t surprised as the TekTurna was not doing much for any of his other patients either. I HATED Tekturna. My Dr told me to throw it in the garbage, and he didn’t think that he would ever prescribe it again, but keep the Diovan and see what my new meds will do.
I have been taking Tekturna for about six months..150 mg. My BP was not controlled so my dr. increased my dose to 300 mg. Since then, the BP is down, but I have swollen ankles and broke out in a rash on both legs from the knees down. I wonder if this is a side effect of the increased dosage or if it is something else. I do not have any cardiac problems and have been checked for DVTs and have none.
Doc recommended Tekturna to help control bp that sometimes got too high. After taking two pills, i was rushed by ambulance to the ER with itching, swollen tongue, red rash, burning in my head, labored breathing, heart palpitations, nausea, and severe weakness. Before taking Tekturna, i was very healthy except for bp. I now require round the clock care. It has been 3 weeks since this episode, and my head yet feels like it is going to explode, and like someone lit a fire in my skull. My vision is blurry, I have chest pains, tightness in my jaws, redness of my face…been rushed to the hospital several times, almost died several times. Three weeks later I am fighting for my life from the effects of this drug. Worst drug ever. If a doc ever prescribes this med to me again, I will turn and run as fast as I can.
elma,
I hope that you informed your doctor and your pharmacist that you are apparently allergic to Tekturna so that they can make a note in your records. Unfortunately, these things are impossible to predict, so there was really no way of avoiding what happened — medication allergies are trial and error. There’s no other way to know.
And of course no doctor is going to prescribe Tekturna for you again. I hope you didn’t dump your doctor over what happened — bad things happen in medicine outside everyone’s control, and it’s ultimately no one’s fault.
Hi,
I’m currently studying tekturna. It is not more efficacious than the drugs currently out there however it seems to have an “arb-like” placebo-like safety profile.
The 24 hour control because of the high TPR and 40 hour half life does make sense… however, i was wondering, in the mass majority of the studies they used to meassure the hypotensive effect they used msDBP and msSBP at trough… 24 hours since the last dose.. so if they found that at trough aliskiren and whatever else they were meassuring up against was the same even if let’s say lisinopril which doesn’t have a vaunted 24 hour control advertisement… what would that mean? I’m not saying to argue, I know that the 2 day fade out is genuine and a definite plus to this drug but day to day, morning hypertension, if in the morning at trough both drugs meassured the same, what would that mean?
I started Tekturna this week. I cannot take other BP meds – ALL gave me pretty bad sides, including NOTICEABLE memory loss!
Here’s hoping Tek works – Dr says we are out of options….
Chotty
I just started Tekturna-blood pressure still hasn’t
come down-running 140/68/62 Very tired-ache all over especially in back of neck
While i dont have high BP (average 140/85)i have just been diagnosed with several coronary narrowings. What about Tekturna as an anti plaque agent.I am researching alternatives to by-pass and stenting procedures.Found an article which describes excellent figures in reducing cholesterol using this drug.Any info?
I started Tekturna today after failing on a bunch of drugs. Also trying CPAP sleeping device in a few weeks (not overweight, have some apnea). Treating my blood pressure has been awful. Wish me luck on the latest. Diovan HCT was a total disaster: big bloated and distended stomach despite vigorous workouts/muscle aches due to potassium loss (which no one told me to replace). HCTZ alone: massive weight gain, especially in stomach. Lotrel: cough so bad I couldn’t sleep. Diovan alone: Huge weight gain, especially with bloated stomach. Coreg: Dizziness so bad I couldn’t work at computer; constant hunger and insomnia. Amlodipine 10: anxiety, depression. Amlodipine 5: somewhat tolerated but hair loss and cough! Micardis: MASSIVE weight gain that have taken me a month to lose with diet and workouts. Is it normal for people’s stomach’s to balloon out on BPMs? My doc says this shouldn’t happen but it is. I cannot seem to tolerate blood pressure medicines. Is this normal? I know I can’t have high blood pressure but the medicines are AWFUL.
I have been on tekturna 1 year now. I had such a hard time on so many other medications with side effects etc. It was a a hard time . I was put on Tekturna the month it became available. This medication is working very well with no side effects at all. I do need to take clondine patch as well- but my BP is now under control- and in the evenings rather low.
I have ben taking tekturna for about a week. I have dizziness and today was so tired, slept most of the day. I am also experience a tight chest and anxiety. I was hoping this drug would work. It seemed to in the beginnin but now I have my doubts. Tried many other bp meds. Need to reevaluate this drug.
Experiencing dizziness and anxiety. I began Tekturna about a week ago. Are these common symptoms? Have tried several other meds no luck. Might try going back on lotrel. The swelling was a pain but I tolerated the drug better than the others.
Linda, one option is to try taking medicine at night if it makes you dizzy by day.
I have been on Tekturna three days now — really too early to tell anything. I have failed on so many drugs due to miserable side effects that I am going to give it at least 2-3 weeks to see if it moves the needle on blood pressure. Hasn’t done anything yet but I am hypertensive so I need to be patient. I did feel depressed today but given some stuff in my life it’s hard to tell if Tekturna had anything to do with it.
In response to Rick Bradleys weight gain comments. I experienced the same thing on the same BP meds. The only one I lost weight on was Lisinopril… but that weight loss was due to it causing me to vomit as many as 15 times per day!
No one has ever told me to replace potassium on any of my meds. I’ve now been diagnosed with hypothyroid and wonder if the BP meds are to blame.
In response to Barabara, lisinopril does not reduce potassium levels. Vomiting does, however! Also, if you are of a “certain age”, like me, fluctuating hormones and hypothyroidism seem to go together for many women. I hope you are feeling better.
I don’t know much, but I do know I was on Norvasc for years and it hardly made a dent in my high bp. Tekturna put me through a month of side effects before I felt normal again, but my blood pressure is perfect now.
I don’t know if there are more natural ways of going about such a change, but shy of finding out this drug has destroyed my internal organs or something, I’ve got no complaints.
Seriously though, knowing what I now know about drug companies, I do with I wasn’t taking such a new drug. It seems like they get approved and the first 5-10 years are just an expanded trial.
As great as Tekturna works for me, I am a little afraid it could be dangerous in other ways, especially since they’re touting it as a “first of its kind” treatment.
I was on Tekturna 300 mg since Jan. I liked it since I didn’t have “fuzzy brain” like I did with others bp meds. About that time, my back started hurting and then near where my gallbladder had been (gone since ’99). I felt like my gallbladder was back. lost 10 lbs, constant diarrhea, couldn’t lay on my right side. All my labs came back normal. Finally went to gastro and over the advice of my regular doc, went off Tekturna. With 24 hrs i felt almost new again. Returned to taking verapamil and now my facial flushing and burning is back. any advice?
I NOTICED HIGH BLOOD PRESSURE IS A SYMPTOM OF HYPOTHYROIDISM AND ALSO PRE-DIABETIS….SYNTHROID CORRECTS THE HYPOTH.PROBLEM AND ELIMINATES THE EFFECTS….HOWEVER,A CONDITION SUCH AS H PYLORI PREVENTS YOUR MEDICINE FROM WORKING EFFECTIVELY…THUS WE HAVE SYMPTOMS OF ORIGINAL DISEASE RE APPEAR….I ASSUME AN INEFFECTIVE DIGESTIVE OR METABOLLIC PROCESS WOULD BE EVEN MORE NEGATIVE TO CONTROLLING BP WITH MEDICINES PRESCRIBED….WHY ISN’T THERE A MEDICAL SERVICE COORDINATING ALL OF THESE POTENTIAL PROBLEMS….ANYBODY CAN PRESCRIBE DRUGS…BUT NO SEEMS TO THINK PAST THAT…WE NEED HELP
Is renin/RAAS completly bad? I don’t think so. It’s a result of the selection of Nature from millions years. Maybe it has some certain unknown important roles. I don’t think Aliskiren is too good. Moreover, it’s a… reverse evolution ^.^
Look:
1.stimulate non-selective alpha&beta receptor (adrenalin) –> non-selective beta (isoprenalin) –> selective beta2 (salbutamol, terbutalin…)
2. non-selective COX inbihitors (aspirin, diclofenac…) –> selective COX-2 (meloxicam, nimesulid…) –> high selective COX-2 (celecoxib, rofecoxib…)
But how about this:
ACE inbihitors –> ARBs –> … DRI (Aliskiren) ??????? ^.^’
Likewise, in the future, there will be have a new bp drug which inhibit the act of… adrenalin ^.^
…
It’s a concession step of the progression
HAHAHAHAHA……..
I started taking 150mg of Tekturna on Friday night. Every day I always drink lots of water because (1) I live in a dry climate to stay hydrated and (2) I have one kidney. Because of the drinking of the water, I have to go to the “john” about every 2-3 hrs. Since starting this medication, I’m lucky if I’ve gone 3 times in one day!!! This REALLY WORRIES me since I’m supposed to drink lots of water to keep my kidney in good working order. I also have not seen any reduction in my BP numbers and I have these terrible headaches just before I get up in the morning – the same type of headaches I got last year just before I ended up losing my kidney!! Is this normal? Should I stop taking the medication? My endocrinologist (I’m a diabetic) prescribed this med for me along with a new diabetes medication that comes with its own long list of side effects (this is a whole other story!!). I also take Clonidine 0.1mg and Avapro (I think 300mg).
I’ve been on Tekturna for two weeks. I’ve tried all the different types of BP medications and have had awful side effects from them all as well as an allergic reaction to Diovan. Tekturna is definitely controlling my BP but all of a sudden on Saturday I started developing a rash–first on my right arm, then my left. Today I noticed that I’m getting a rash on my legs from the knee down. HELP!!!! What should I do? The Tekturna is working on my BP and other than the rash, I’m not experiencing any other side effects.
That’s an allergic reaction… you should stop taking the Tekturna and contact your doctor. In terms of immediate severity, allergic reactions are more dangerous than chronic hypertension.
Has anyone started taking 150mg of Tekturna and then increased to 300mg of Tekturna? If so, what happened? Any sort of side effects? Are there any side effects that are not listed on the Tekturna website that people are experiencing? If so, what are they? Do you find that Tekturna controls your blood pressure all day long or are there certain times of the day that it goes higher? I’m finding that Tekturna is controlling my pressure really well until I go out to do physical activity during the afternoon; when I take my pressure upon return, it’s up—then a few hours later, it goes back to an acceptable level. Looking forward to hearing from as many people as possible.
After 3 horrible months of hacking cough, nausea,sleepless nights, extreme lethargy, running nose, belly ache, distended belly…I discovered on Monday that I wasn’t having the World’s longest allergy attack or flu, but that I was having a reaction to lisinopril. So, I researched it when I got home, and the reviewers described all of the same symptoms. Mine came on gradually and I had been in an accident, so I just didn’t put it all together.
Went to visit my neighbor who just got home from the hospital today after even MORE tests after five months of seeing doctors for heartburn that wasn’t responding to anything, diahrrea, coughing, hoarseness, swollen belly, leg pains, extreme lethargy, vomiting, sleeplessness and depression. Only to figure out this morning that she was the victim of this new wonder drug–tekturna, which she was taking 300 mg a day of. She lost 27 pounds that she could ill afford to lose.
Needless to say, she won’t be taking any more.
My point is, what is the solution–especially when all of my research shows the companies and the press downplay the side affects on their sites, and the public is lulled into thinking these drugs are OK and if not, something is wrong with THEM!
Doctors who dispense these meds need to be more thorough with their patients in explaining the possible side affects–and patients should read everything that comes with their meds from the pharmacy. I have found so many patient reviews outlining the difficulties with the two aforementioned meds and teckturna’s sister med, diovan. And the laundry list is incredible and so strikingly similar in all of them. Obviously none of us were their test patients.
From now on, I’m not taking anything without checking it out and having a conversation with my doc and pharmacist.
After searching for days to learn of patient responses to Tekturna, I finally came across this site. Thank you.
I had severe angioedema 12 years ago that swelled my throat so much that I could not breathe. The miracle drug honey, yes, bees honey, saved me. If I would have waited for an ambulance I would have died (could not phone for one anyway because my throat was so swollen I could not utter a sound). Don’t ask me what I was on at that time — was given a new BP med every week.
Was successfully on Lisinopril for the past 4 years but upon taking Sulfasalzine for arthritis my eyelid swelled. The allergist said it wasn’t the Sulfa but the Lisinopril so I was taken off and put on Diovan. My BP readings soared, as high as 200/100. Never went down. Then another M.D. added Normadyne. What junk! Started itching all over, especially my scalp. Taken off and put on Norvasc + Diovan. Still felt like crap. In the meantime the eye swelled up again, this time attributed to the Sulfasalazne. Finally taken off Sulfa so I asked about going back to Lisinopril. Instead I was told to stop everything and take Tekturna. I am really afraid to take something so new that there hasn’t been enough time to give it a thorough investigation. I am beginning to think it is just something hyped up to profit the big Pharms.
I can understand why your physician prescribed tekturna because he wanted to give you something which had the potential for the least interactions with other products. You should be thankful that your physician is prepared to consider new and excellent products and not experiment with such things as betablockers, a blockers and diuretics.
You have a good physician.
I have now been on Tekturna for a little over a year. Zero side effects and it is working well. I had tried so many other types of BP meds with so many side effects and little results that my cardiologist asked me to try tekturna. I was hesitant to try a new drug.. and I still worry a bit but I am doing well and all labs came back looking great.
DRUG REP ALERT.
You are a drug rep for Tekturna?
No, but David reads like one.
RJS,
I started reading thru the threads on Tekturna and you seem very knowledgable. I felt better reading your comments thanks. I am doing so well on Tekturna I just worry as it is so new- but I figure all drugs are new at first and so many do work. I wish I had found this thread a year ago when I had been put on so many meds I lost count with awful side effects and intolerances.
Much earlier on these threads RJS mentioned that RAAS drugs were safest to control BP. What are RAAS?
I just hate BP medication. This Tekturna worries me because I am so sensitive to chemicals and my doctor treats me like I am some kind of a needless worrier. However, I will NEVER forget my awful experience when my throat swelled up and I felt like I was being choked to death from what I think was a CCB.
Some people posted earlier comments about some scarey adverse side effects with Tekturna. I wish that they would give more details if they found something that helped them out.
I have read Dr. Weil (who is opposed to Tekturna) and Dr. DeVries and Dr. Sinatra who have written books about alternative treatments like diet, exercise, etc. But, with my high BP I need something else. I take fish oil, exercise, good diet, etc., etc. It is weird that the docs just keep changing the pills and say “come back in 2 weeks”. What if I have an adverse side-effect before that?
Nancy,
I too had similar problems- Sudden onset very hard to control BP and put on medication after medication with severe side effects and uncontrolled BP. I had a corneal bleed and lost some vision in one eye ( did return) . During this time I also had surgery and was thrown into menopause rapidly so I was anxious, flashing and thrown into my first ever depression. It was trial and error time and I had a steep learning curve. I was put on every kind of BP med Calcium channel and Beta blockers, ACE, ARBs, Diruetics,Hormones, antidepressants etc. The intolerances and mixing of medications was a nightmare. I am a person who seldom drinks, avoided any kind of drug and preferred herbs when I could , great diet , excercised, bought organic foods, even drive a prius ;-)
I had severe BP episodes of where my BP would spike very high BP on meds for no reason so they began looking for a specific type of tumor- I was scanned, probed and put through every type of test you can imagine- Nothing could be found. Thank goodness for good insurance!
They finally put me on the clonidine patch and things started to come down but I needed more help. I tried hawthorne and other herbs with no results. Doctor gave me Tekturna, I was worried and expressed that but it worked within 2 weeks and had no side effects. I weaned myself off the antidepressant and all other medications except the 2 BP meds. I am amazed and have no clue why Tekturna worked for me when the ACE or ARBs did not. I am so much better.
I did go see an accupuncturist at the same time and continue to see her every 3 weeks. I was very skeptical but I am amazed at how much it is helping. I started meditating and going through daily relaxation technigues. Also new.
I am greatful, yet still cautious. I go in next week for my 6th month check up with the cardiologist. Been on Tekturna 1 year now. Any questions I should ask?
Debbie
Is anyone else experiencing the stomach discomfort caused by Tekturna and if so, what are you doing about it?
Stomach discomfort: Not sure what type of stomach discomfort you are having. It makes me go to the bathroom (absolutely the opposite of constipation) and I was told to take Immodioum. More drugs! Said that Pepto Bismo didn’t work as well.
I do have feelings of heartburn. I take Zertec with the the Tekturna.
Just had the Metabolic panel blood test and everything was normal. I think my high BP might be totally stress induced + strong family history of hypertension, stroke and heart attacks.
BP was getting a bit better but this morning it was 176/86, so its the same old, same old.
Thanks for answering so quickly!!! I get pains in my stomach/lower abdomen. I’d hate to have to take MORE drugs to deal with it!!! I know just what you mean…. I think my hypertension is caused by the same thing as yours…I can’t lose any weight,(I weigh under 100 lbs.), I can’t alter my diet,(I eat a heart healthy diet), I exercise at least once a day if not more…. How long have you been on the Tekturna? I find it controls my BP for probably 20 out of every 24 hours… I’m on the 150mg tablet… Judy
Judy,
Yes, I had the stomach problems, also felt like I had the flu all of the time along with dizziness and heart palpitations. My solution was to quit taking Tekturna. Finally, what I think was the placebo effect, quit working and BP went up so I went to the Dr and said no more, this stuff is crap. He agreed and said that was basically the response from all of his patients so throw it in the garbage. He then put me on Exforge (Diovan and Norvasc). It worked, but still felt like a milder case of the flu, edema in the legs and suddenly started going to the bathrom 10-12 times a night (no matter when I took the tablet). Still had the heart palpitations, maybe even more. It may have been the Exforge, maybe the lack of sleep. Finally told the Dr and he put me back on the Diovan that I had successfuly taken for years only a higher dosage. Hallelujah, edema was gone in two days and so was the nocturia. My BP is also 119/81 average. The point is, keep going to your Dr until you find the right thing. Everyone does not need the same thing. I hated Tekturna and Exforge, other people hate Diovan. My body is not your body and vice versa. Just keep trying until you find what works and I can almost guarantee that at some point you will have to try something else again. Good luck.
Yes I think we need Tekturna. I have tried so many blood pressure medicines and had bad side effects to full
blown allergic reactions to them. I am also alergic to sulfa so
can’t take diuretics. So far Tekturna is working fine.
Sue,
I am also allergic to sulfa drugs but also couldn’t take diuretics because I have Sjogrens – a syndrome that causes me to have extremely dry eyes, throat etc… I couldn’t take medications that dry me out further. And like you Tekturna is working well after a long period of terrible side effects and poor results with so many others. How long have you been on it? What does schedule are you on?
Debbie
Has anyone had any experience with taking something like Xanax or Vallium or an anti-depressant to lower the stress levels that might be causing the spike in blood pressure?
On occasion, when I haven’t been able to sleep I take 1/2 of the lowest dose of Xanax. It knocks me out right away. However, since I am sensitive to everything I haven’t tried a stronger dose or a daily 1/2 dose.
I know we are all different but does anyone know of a medication that might safely help in that respect? Or, is meditation or massage better?
Nancy,
During my 2 years now with high BP I have tried a few new strategies in addition to medications. I have had very good results – slowly however and not enough to get off my BP meds but have been able to reduce the dosage. I was able to get off all the other meds. Originally I was a skeptic of meditation and acupuncture but my GP , cardiologist and then therapist recommended both due to problems I was having with increased anxiety ( also new) in part due to going thru the ‘change’after a hysterectomy and hormonal fluctuations. The interesting thing is that the severe hot flashes, sudden ‘malignant’ high BP ( meaning it was not controlled) and severe anxiety all happened around the same time period. I was a mess. In emergency rooms, up at Stanford etc. AS I mentioned before the arsenal of medications were used and side effects were awful and BP was not controlled. I was also put briefly on Lexapro and xanax which helped as I learned other strategies. I was off the lexapro in 3 months. I take xanax like you as needed at the lowest dose. I am not on any hormone therapies . Anyway, I began meditating and using a device called an EMWAVE to help me learn how to breath and calm myself. INCREDIABLE results- my GP and cardiologist bought one and went to trainings about it. I then moved into daily relaxation and meditation with positive statements and my BP can now drop up to 20 points when I have a high ‘spike’. It has taken me a year to get to this level. I also started accupuncture a year ago. Again skeptical but wanting to get off the meds. I am impressed and surprised. I go religiously and am amazed at how well I am doing and how it has helped. I have had slow but steady improvement.
I also have troubles sleeping and now use that time to meditate. Overall, meditation and accupuncture has made a big difference.
Debbie
was bumped up to 300 mg by my Doctor after a bp reading of 160/90/74 I take diovan and toprol xl also. After 1 week at 300 mg my lower back and right side where my gall bladder used to be started to ache. skipped a day of Tekturna and the pain diminished. BP was averaging 150/84/70 yesterday so I need to do something to get it back to acceptable levels
After going for a BP check on Thursday, my BP was 180/72 so my Tekturna was increased from 150 to 300 with the HCT. I was given samples, but, I don’t want to take it. Look at the RXList site about Tekturna HCT, it is really bad stuff.
On top of that, the nurse does the BP check and then reports to the cardiologist. I never see the cardiologist, just the nurse and SHE decides on the treatment, then contacts the MD to confirm.
No more! I am seeing another MD Tues if I don’t have a stroke over the weekend. Wish me luck!
A daily dose of 150 mg of Tektkurna for a year to lower blood pressure has apparently caused gout with severe pain in both big toes and the right index finger. Has anyone else developed gout as a result of taking this drug?
I would be looking for other causes of gout before pointing the finger at Tekturna.
HELP! MY WIFE HAS HAS ISSUES WITH HIGH BLOOD PRESSURE FOR THE PAST 7 YEARS, SWITCHING MEDICATION ON AND OFF DUE TO SIDE EFFECTS AND NOT WORKING AFTER SEVERAL MONTHS.
ABOUT SIX MONTHS AGO OUR DOCTOR RECOMMENDED TEKTURNA 150 MG/DAILY AND NOW AFTER SEVERAL MONTHS MY WIFE IS EXPERIENCING VARIOUS SIDE EFFECTS TO INCLUDE HEADACHES, NUMBNESS IN HER ARMS AND LEGS, AND A TINGLING FEELING CONSTANTALLY ALL OVER HER BODY.
HAS ANYONE ELSE NOTICED THESE TYPE OF EFFECTS/REACTIONS AFTER TAKING TEKTURNA AFTER SEVERAL WEEKS?
I have well controlled BP- using Norvasc (10mg), toprol XL (200mg) and Diovan hct 320/25). My doc said I should try Teknurna which I have ben on for about amonth. My question is – I have 4 months of Diovan left before I switched to the Tekturna. Can I go back to use up the Diovan ( I am getting close to donut hole) and then go back to the tekturna?
Also, I have a post nasa drip for about 4 months and doc has had me on antibiotics which did nothing – now I am on nasonex and Singulair. Can this be caused by any BP meds?
Thanks — Steve
One poster taking tekturna reported muscle pain. I am taking tekturna hct 300/25 together with dynacirc cr 10 mg.
I have noticed a pronounced increase in lower back pain and joint pain since teckturna was added to my daily regimen. I am wondering if this drug combo is a wise decision.
One of the difficulties with multiple BP meds is the absence of side effects on drugs taken in combination.
Anyone else out there experiencing pain with tekturna?
I have taken 300 mg of Tekturna for about 6 months. Previously I had been given Divan, Lisinopril, etc, and had almost immediate side affect. During the last two weeks my muscles been painful and sor and my low back has constantly ached. When I lie down or sit down I am in pain. Paint medications do no help. This is Sunday and tonight I will not take the Tekturna. It has been my policy not to take any medication unless it has been on the market for five years or longer. I will stay with this in the future.