This man, Carlos Camejo — seen holding his own death certificate — woke up during his own autopsy after a car wreck:

Carlos Camejo, 33, was declared dead after a highway accident and taken to the morgue, where examiners began an autopsy only to realize something was amiss when he started bleeding. They quickly sought to stitch up the incision on his face.

“I woke up because the pain was unbearable,” Camejo said, according to a report on Friday in leading local newspaper El Universal.

Ouchies. I guess they’re not as thorough in other countries when it comes to pronouncing someone dead…

He should go as a vampire for Halloween. ;)

(Images preserved in order to stave off the inevitable Reuters link rot.)

She swerved to avoid the cup of soda and drove into the side of the pharmacy instead. How she got up on the MASSIVE SIDEWALK is anyone’s guess.

Just bloody brilliant.

Today’s Close to Home reminded me of something we used to do to take the edge off the sauce when my dad was having heartburn problems: a small amount of baking soda into the sauce while it was simmering.

Baking soda is sodium bicarbonate, also available in tablet form for — you guessed it — heartburn. Certainly though, Tums (calcium carbonate) are far more common than soda bicarb tabs. I suspect this is due to marketing more than anything else.

I wonder if McPherson knew he was unintentionally close to a mark?

[tags]Lasagna, heartburn, cooking[/tags]

The Ole’ Apothecary writes:

I believe that the continuing education (CE) requirements for U.S. pharmacists are woefully inadequate. They should be increased, in both number and difficulty.

To start with, the number of required CE hours should be doubled in every state. They have not been changed in 30 years. Also, at least half of these hours should be live, at least to get us to interact with educators, and, at most, to get us to interact with our peers in the profession.

I couldn’t agree more. I think pharmacists should have to take a periodic exam to assure basic clinical competence as well. I’ve had pharmacists ask me to do their CEs for them, which I find appalling behavior. It is my opinion — and after 6 years behind the counter, I’m not as naive and enthusiastic as I once was — that you should take pride in your profession, and that you should want to keep up with developments in the field of medicine. Even non-drug therapies, in my non-humble opinion. You didn’t go to school to learn to count to 30 and slap a label on a bottle. Any jackass can do that, and every jackass with half a clue learns the necessary behavioral tricks to survive standing behind that counter, too.

(Well, maybe you did go to school to learn to count to 30 because you thought that since you planned on standing behind that counter, you might as well make some money while doing it. That’s alright, I guess, but I wouldn’t want you as my pharmacist. No offense or anything.)

What boggled my mind were some of the comments left on TOP’s entry. By pharmacists. The vitriol that follows isn’t directed at these people specifically, but rather at the lackadaisical attitude in general that many pharmacists have towards keeping up with their profession.

Even if you cheat like I do and go straight to the questions without reading the program, you still get SOMETHING out of it because you still have to look for the answers.

Well I am a 63 YO RETIRED Pharmacist and honestly I never learned much, if anything, from any of the CE courses I have taken over the years…

All were a total WASTE of time..

Look, I know CEs are seen as an onerous chore. (“OMG! It’s December and I haven’t finished gotten all of my credits yet! … Will you do this CE for me?”) Maybe you’ve got kids, and your family takes up your free time. In retail there’s that fantastic work-home life divide. Work stops as soon as you leave the pharmacy, and the retail environment isn’t the place to try to learn anything, unless you work in the slow store. Frankly, this divide between work and home is no excuse to not stay current. You’re a professional, for fuck’s sake, not a factory worker. This is one of the things that sets professionals aside from non-professionals — you have to make some effort on your own to stay current. Whether or not you are paid for the time you spend is not even a question. It’s just something you do.

I don’t believe for one minute that you actually retain anything that you “go back and find” to get the correct answers. Not for more than a day or two, in any meaningful detail.

I’m bringing this up now because one of the pharmacists I work with recently gave a patient the wrong answer. (Which may breed another entry for later about stepping on toes.) It was a basic question about statins — and she got it wrong. It wasn’t even a hard question. It was “When is the best time to take simvastatin?” It doesn’t matter how busy your pharmacy is. If you can’t answer the most basic question someone could ask about the most popular HMG-CoA reductase inhibitor in America, you’re doing something wrong. And she’s in her early 30s — nowhere near retirement age.

I cringe at the thought of the 63 year old retired pharmacist who never learned anything doing CEs. Unless you’re reading journals, and staying current of your own accord — which you’re probably not — you probably didn’t know much about modern medicine while you were still working. How many major classes of drugs came out since you graduated pharmacy school?

Well let’s see. There’d be the PPIs, statins, quinolones and fluoroquinolones, macrolides (things have changed a lot since erythromycin), atypical antipsychotics, SSRIs, COX-2 inhibitors, AIDS drugs, the entire field of asthma management, ARBs, T2DM management… I could keep going. Without even going near the biologics. ALL of the drugs in these classes have their basic similarities, but equally importantly, their differences.

Wait a minute! That’s basically the entire list of the top 200 drugs prescribed in America! You learned about all these things when you were in school? Are you up on them? Even the basics? Gee, a statin’s for cholesterol… whoopty freakin’ do. You’re a goddamn genius.

Do you even know what cholesterol actually is?

And not to mention that our understanding of the mechanisms of action of some older drugs have changed since you were in school. Theophylline is an old drug that springs readily to mind as a drug about which our understanding has changed over time. Perhaps since you first learned about it all those years ago.

For shits and giggles last night, I went back to some older issues of the clinical publication my chain puts out. My mind was boggled at how much our understanding has changed about even “basic” problems like ADHD and depression in just 8 short years. Almost nothing is hammer -> nail anymore.

Just like formal schooling, you get out of CEs what you put into them. I have no doubt that a great many of them are useless. CEs may not be an ideal answer, but they do serve, if you make the effort. Some of the information is undoubtedly redundant. Some of it you undoubtedly learn by osmosis. But I guarantee you that if you pick up a CE and really read it, you will learn something.

Plagakis would probably say that “we’re all clinical”. The Ole’ Apothecary asks if some are more worthy than others.

The answer is “yes” but it doesn’t matter if the letters after your name are “RPh” or “PharmD”. Some are inevitably more clinical than others — and that’s okay. But there needs to be some basic standard of clinical competence, otherwise you’re just a glorified pharmacy technician with some extra liability padding and a key to the safe who takes home a fat paycheck every other week.

And if you’ve never learned anything at a CE, you should be looking in the mirror for the reason instead of pointing a finger at the system.

These were drop-shipped yesterday afternoon:

A couple of weeks ago, I was detailed by GSK. Unlike The Angry Pharmacist, I don’t hate drug reps. The GSK guy isn’t a busty blonde who brings us cannolies and only visits at lunchtime. He’s actually a genuine human being, and he’s probably old enough to be my dad.

But on his last visit, he did something that rubbed me the wrong way: he asked me to fill out these cute little forms and send them to the doctors to get them to switch to the controlled released versions of carvedilol:

Yeah okay, buddy. How about no? I like you well enough, but geeeeze. Your form is pretty, but a reversal of it would be more useful: seniors sure do like those generics that’re covered even during the donut hole…

Needless to say, I threw the stack of forms in the trash without showing anyone else. As the person who makes the most therapy recommendations, no one but me would have a use for them anyway. Even if they weren’t complete bullshit.

—

On a related note, I’m waiting for the day drug companies get a clue and make writing the original, IR version of a drug more troublesome to prescribe than the inevitable extended-release forms. Call it “Coreg IR” the first time around, and then call your extended-release, patent-protected, evergreened, overpriced bullshit version plain old “Coreg.” As though it were Coreg As It Was Meant To Be — like that marketing crap Sanofi-Aventis tried with Ambien. (Zomg, we should never have made Ambien because Ambien CR is soooooo much better. Ugh.)

That’ll work better than your fancy brochures, ridiculous therapy change forms, and formulary negotiations combined.

[tags]GSK, Coreg, carvedilol, marketing[/tags]

…by buying me food.

They were delicious, I can assure you. Thanks, Merck, for bringing a fantastic local bakery to my attention! :D

One of TAP’s bullet points made me chuckle. It also jogged a memory.

The patient who you thought you filled that Rx correctly for ended up having another last name and the same birth-date as someone else in your system. Of course they don’t tell you this until after they have received the Rx and loudly proclaim that you filled it for the wrong person with a store full of people. I mean aren’t we supposed to know that her full name is Maria Consuelo Rodriguez Maravilla Hernandez Guadalupe AIAIAIAIA ARRIBA?

We have one patient in one of my pharmacies — yes, they’re mine — that has two names.

Two completely different names. No motifs. No variations on a theme. One day she’s Maria Gomez and the next day she’s Elisa Rodriguez. It’s fucked up. What’s even more fucked up is that Maria doesn’t know Elisa’s name, and vice-versa. She has to read it from the bottle that she wants refilled, and God help you if she doesn’t have the bottle that day. But even more mind-blowing than this is that I’m the only person in over a year to actually put the other name in each of her two profiles. Yeah. Wrap your brain around that one, if you can.

This woman takes an SSRI, but that’s it in terms of psych meds, so I have no idea what her deal is. I wouldn’t even want to guess. Naturally, she can’t speak English except for “15 meenoo? O-K,” so I’ll never find out, but she is terribly nice, which does get her some brownie points. I’ll take a nice idiot over a smart asshole any day of the week. Not that she’s an idiot — I strongly suspect she has some untreated psych condition. (Surely it can’t be undiagnosed? We can’t be the only ones who haven’t figured out that something’s not quite right.)

Thankfully she is starting to prefer one name over the other, so I guess we’re making some progress. Or maybe it’s a seasonal thing? Now that it’s after Labor Day she’ll go back to being Elisa… :suicide:

Do zey need adjusting?

Heh heh…

Merck and Schering-Plough are in bed together, again. (One wonders if a merger will be the climax of their collaborations somewhere down the line?) This time it’s their new combination of loratadine (Claritin) and montelukast (Singulair) which was accepted for review by the FDA on August 28. In my opinion, it’s only a matter of time before the two companies are given the green light to start selling it.

This combo is not unlike their Vytorin arrangement, which is actually a pretty decent combination both therapeutically and financially: Vytorin is no more expensive than Zetia by itself, which makes it a good deal for consumers and insurers alike. (And there’s also the more mundane fact that there’s one less pill to take, and the fact that ezetimibe is of questionable value when prescribed alone.)

Because Claritin is now OTC, it is simultaneously more and less valuable to Schering-Plough. Less valuable because you can’t charge as much for it as you could when it was Rx-only because no one would buy it — and more valuable because you’ve got a potential market limited only by the number of people in the United States. I know I recommend (generic) Claritin pretty regularly. It works well for most people, myself included.

If the pricing is done following in the footsteps of Vytorin — which I suspect it will be — it’ll be a nice little niche drug for the two companies, and it’ll save consumers money, if not insurers. I don’t ever see it being a blockbuster like Vytorin, for obvious reasons.

The inobvious

One thing struck me about this deal after some thought, and it’s the new reciprocity between the two companies: Vytorin is inherently more valuable to Schering-Plough because their drug ezetimibe (Zetia) is still protected by patent, whereas Merck’s contribution — simvastatin — is not. With this new drug, the roles will be reversed. I don’t know what this means in terms of dollars and cents, but Merck’s got to be breathing a bit easier now that they’re on more equal footing with their partner.

[tags]Merck, Schering-Plough, Claritin, Singulair[/tags]

Novartis has gotten their pointless direct renin inhibitor approved by the European equivalent of the FDA.

How utterly snooze-worthy. Now you Europeans can waste your tax dollars money on the drug, too! Hooray!

Bonus Tekturna story:

Doctor writes a prescription for Tekturna for one of his patients. (One of our drug delivery guys, actually.) Gives him a free sample card, even though he doesn’t have insurance and thinks he’s doing him a favor. He gets 30 Tekturna for free, and the next month rolls around. That’ll be $100, please, even with the employee discount I gave him because he amuses me.

He almost shit a brick.

Remember, folks: giving patients a FREE SAMPLE is great, but it’s a complete WASTE OF EVERYONE’S TIME if they are without insurance or if their insurance doesn’t cover it.

Mr. Delivery Guy comes back a week later with a prescription for lisinopril, after I write him a note to give to his bonehead physician.

Sometimes I wonder…

[tags]Tekturna, aliskiren, Rasilez[/tags]